Wernicke-Korsakoff syndrome

Wernicke-Korsakoff syndrome stems from causes similar to those of beriberi, depletion of the body’s stores of thiamine (vitamin B1) from many years of malnutrition due to alcoholism. Symptoms include anemia, anxiety, depression, and confusion. About 40% of those affected also have anemia as a result of folic acid deficiency. Weekly injections of thiamine and daily doses in capsule form can be used.

Korsakoff’s psychosis, a disorder stemming from destruction of nerve fibers connecting brain cells, is a serious neurological/psychiatric disorder seen in advanced alcoholism. It stems from the effects of the acetaldehyde that builds up in the liver and spills over into the bloodstream, where it creates free radicals that cause damage throughout the body. In the brain it can impair cellular communication by injuring the nerve fibers connecting cells. The prescription drug Hydergine stimulates regrowth of these damaged nerve fibers. The most effective form of Hydergine comes in tablets, which can be placed under the tongue for immediate absorption. Ask your doctor about Hydergine if you feel you need help in this area.

 


Signs, symptoms & indicators of Wernicke-Korsakoff syndrome

Symptoms - Mind - General  

Periods of confusion/disorientation




Conditions that suggest Wernicke-Korsakoff syndrome

Circulation  


Mental  


 



Risk factors for Wernicke-Korsakoff syndrome

Symptoms - Food - Beverages  

Being a recovered alcoholic



 

Moderate/high alcohol consumption




Wernicke-Korsakoff syndrome suggests the following may be present

Circulation  



Wernicke-Korsakoff syndrome can lead to

Mental  


 


Key

Weak or unproven link
Strong or generally accepted link
Proven definite or direct link

Glossary

Wernicke-Korsakoff

Wernicke-Korsakoff syndrome stems from causes similar to those of beriberi, depletion of the body's stores of thiamine (vitamin B1) from many years of malnutrition due to alcoholism. Symptoms include anemia, anxiety, depression, and confusion. About 40 percent of those affected also have anemia as a result of folic acid deficiency.

Thiamine

(Vitamin B-1): A B-complex vitamin that acts as a coenzyme necessary for the conversion of carbohydrates into glucose, which is burned in the body for energy. It is essential for the functioning of the nervous system.

Anemia

A condition resulting from an unusually low number of red blood cells or too little hemoglobin in the red blood cells. The most common type is iron-deficiency anemia in which the red blood cells are reduced in size and number, and hemoglobin levels are low. Clinical symptoms include shortness of breath, lethargy and heart palpitations.

Anxiety

Apprehension of danger, or dread, accompanied by nervous restlessness, tension, increased heart rate, and shortness of breath unrelated to a clearly identifiable stimulus.

Folic Acid

A B-complex vitamin that functions along with vitamin B-12 and vitamin C in the utilization of proteins. It has an essential role in the formation of heme (the iron containing protein in hemoglobin necessary for the formation of red blood cells) and DNA. Folic acid is essential during pregnancy to prevent neural tubular defects in the developing fetus.

Korsakoff's Psychosis

Korsakoff's psychosis, a disorder stemming from destruction of nerve fibers connecting brain cells, is a serious neurological/psychiatric disorder seen in advanced alcoholism. It stems from the effects of the acetaldehyde that builds up in the liver and spills over into the bloodstream, where it creates free radicals that cause damage throughout the body. In the brain it can impair cellular communication by injuring the nerve fibers connecting cells.

Free Radical

A free radical is an atom or group of atoms that has at least one unpaired electron. Because another element can easily pick up this free electron and cause a chemical reaction, these free radicals can effect dramatic and destructive changes in the body. Free radicals are activated in heated and rancid oils and by radiation in the atmosphere, among other things.

Hydergine

The prescription drug Hydergine stimulates regrowth of damaged nerve fibers in Korsakoff's psychosis. The most effective form of Hydergine comes in tablets, which can be placed under the tongue for immediate absorption.

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