The largest study of hydrazine sulfate (740 cancer patients in the Soviet Union) found that hydrazine sulfate produced stabilization or regression of the tumor in 50.8% of the patients. Other studies have not found similar results but may have been flawed. According to Dr. Joseph Gold, who pioneered this use of hydrazine sulfate, there are few side effects - mild numbness of the digits, nausea and slight drowsiness. Nerve inflammation can be cause by long-term use, but this can be diminished or eliminated by taking vitamin B6 or reducing the dose of hydrazine sulfate.

NOTE that it is not approved by the FDA for cancer therapy and, if taken, should be used under the direction of your doctor. If a special diet (discussed below) is not adhered to, it can be useless at best and fatal at worst. Despite the care that must be taken, many people have found it helpful.

Hydrazine sulfate is usually administered orally to cancer patients in 60mg capsules or tablets, approximately one to two hours before meals. It is given at first once per day for several days, then twice, then three or four times daily, depending on the patient's response and the physician's judgment. On such a regimen, many terminal and semiterminal patients have derived considerable benefit, although patients in the early stages of the disease derive the most benefit from the treatment.

Approximately half of the patients to whom the drug is properly administered in the early stages of the disease show an almost immediate weight gain and reversal of symptoms; in some instances, the tumor eventually disappears. The common types of cancer most frequently reported to benefit from hydrazine sulfate therapy are recto-colon cancer, ovarian cancer, prostatic cancer, lung (bronchogenic) cancer, Hodgkin's disease and other lymphomas, thyroid cancer, melanoma, and breast cancer. Some less common types of cancer also benefit.

WARNING! Hydrazine sulfate is a monoamine oxidase (MAO) inhibitor and is incompatible with tranquilizers, barbiturates, alcohol and other central nervous system depressants. Foods high in tyramine, such as aged cheeses and fermented products, are also incompatible with MAO inhibitors. The use of tranquilizers, barbiturates and/or alcoholic beverages with hydrazine sulfate destroys the efficacy of this drug and increases patient morbidity.

"Whether hydrazine sulfate should be used in conjunction with other agents seems to be dependent on whether these agents are doing the patient any demonstrable good." says Dr. Gold. "In the instances in which these agents have been doing good, hydrazine sulfate should be used in conjunction with them. However, and especially with those cases on toxic drugs, in instances in which the drugs have been doing no evident good, it is probably best to withdraw such drugs and use hydrazine sulfate alone."