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In order to confirm whether hydrochloric acid (HCl) is needed, the HCL trial is used to assess stomach digestive function by evaluating the integrity of the stomach lining and its mucous barrier. There is a correlation between a strong barrier and a strong digestive function (i.e. acid and enzyme production). HCL capsules are taken in increasing doses with substantial meals until symptoms of excess manifest. A typical program would be:
Individuals with very moderate HCL deficiency generally show rapid improvement in symptoms and early signs of intolerance to the acid. This typically indicates a return to normal acid production. Supplementation levels are reduced accordingly, even to the point of no longer requiring the supplement. If maldigestion symptoms return, supplementation can be restarted. Individuals with low HCL/Pepsin may not respond as well to botanicals and supplements, so to maximize benefits, it is important to continue HCL supplementation. Administration of HCL/Pepsin is contra-indicated in peptic ulcer disease. Capsules should be swallowed whole, not emptied into food or water. It's important to note that hydrochloric acid should not be used at the same time as aspirin, Butazolidin, Inodicin, Motrin, or any other anti-inflammatory medication. |
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![]() | ![]() | May do some good |
![]() | ![]() | Likely to help |
![]() | ![]() | Highly recommended |

GLOSSARY
Antacid: Neutralizes acid in the stomach, esophagus, or first part of the duodenum.
Anti-inflammatory: Reducing inflammation by acting on body mechanisms, without directly acting on the cause of inflammation, e.g., glucocorticoids, aspirin.
Enzymes: Specific protein catalysts produced by the cells that are crucial in chemical reactions and in building up or synthesizing most compounds in the body. Each enzyme performs a specific function without itself being consumed. For example, the digestive enzyme amylase acts on carbohydrates in foods to break them down.
Hydrochloric Acid: (HCl): An inorganic acidic compound, excreted by the stomach, that aids in digestion.
Milligram: (mg): 1/1,000 of a gram by weight.
Nausea: Symptoms resulting from an inclination to vomit.
Peptic Ulcer: A general term for gastric ulcers (stomach) and duodenal ulcers (duodenum), open sores in the stomach or duodenum caused by digestive juices and stomach acid. Most ulcers are no larger than a pencil eraser, but they can cause tremendous discomfort and pain. They occur most frequently in the 60 to 70 age group, and slightly more often in men than in women. Doctors now know that there are two major causes of ulcers: most often patients are infected with the bacteria Helicobacter pylori (H. pylori); others are regular users of non-steroidal anti-inflammatory drugs (NSAIDS), which include common products like aspirin and ibuprofen.
Protein: Compounds composed of hydrogen, oxygen, and nitrogen present in the body and in foods that form complex combinations of amino acids. Protein is essential for life and is used for growth and repair. Foods that supply the body with protein include animal products, grains, legumes, and vegetables. Proteins from animal sources contain the essential amino acids. Proteins are changed to amino acids in the body.
Stomach: A hollow, muscular, J-shaped pouch located in the upper part of the abdomen to the left of the midline. The upper end (fundus) is large and dome-shaped; the area just below the fundus is called the body of the stomach. The fundus and the body are often referred to as the cardiac portion of the stomach. The lower (pyloric) portion curves downward and to the right and includes the antrum and the pylorus. The function of the stomach is to begin digestion by physically breaking down food received from the esophagus. The tissues of the stomach wall are composed of three types of muscle fibers: circular, longitudinal and oblique. These fibers create structural elasticity and contractibility, both of which are needed for digestion. The stomach mucosa contains cells which secrete hydrochloric acid and this in turn activates the other gastric enzymes pepsin and rennin. To protect itself from being destroyed by its own enzymes, the stomach’s mucous lining must constantly regenerate itself.
Teaspoon: (tsp) Equivalent to 5cc (5ml).