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Foods that are riper or have been longer standing tend to have higher tyramine content than fresh or freshly-prepared foods. Thus a piece of fruit that is fresh and firm may be well tolerated, but a ripe or especially over-ripe piece of the same food may provoke a serious reaction. Furthermore, bacterial action on protein sources such as meat and soy products can cause an increase in the food's tyramine levels. In summary, the caution regarding foods high in tyramine is that firm and fresh is more likely to be safe than over-ripe or over-exposed to potential bacterial overgrowth.
High tyramine-containing foods
authors of this study concluded that pizzas from large chain commercial outlets are safe for consumption with MAO inhibitors. However, they recommended caution when ordering from smaller outlets or with gourmet pizzas that may use aged cheeses. All soybean products should be avoided. |
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GLOSSARY
MAO: Abbreviation for a breakdown enzyme monoamine oxidase. A MAO inhibitor blocks the action of monoamine oxidase, thus raising the levels of the monoamine neurotransmitters such as norepinephrine, epinephrine, dopamine, and serotonin - which have significant effects on mood and behavior. Epinephrine, norepinephrine and serotonin are normally deactivated by MAO-A while dopamine and phenylethylamine are normally metabolized by MAO-B.
Protein: Compounds composed of hydrogen, oxygen, and nitrogen present in the body and in foods that form complex combinations of amino acids. Protein is essential for life and is used for growth and repair. Foods that supply the body with protein include animal products, grains, legumes, and vegetables. Proteins from animal sources contain the essential amino acids. Proteins are changed to amino acids in the body.
Tyramine: An amino acid synthesized in the body from the essential amino acid tyrosine that has a sympathomimetic action and is derived from tyrosine.
Yeast: A single-cell organism that may cause infection in the mouth, vagina, gastrointestinal tract, and any or all bodily parts. Common yeast infections include candidiasis and thrush.