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| Elevated Testosterone Level, Female |
Last updated: Jul 22, 2008 |
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Elevated Testosterone Level, Female |
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Signs, symptoms and indicators | Conditions that suggest it | Contributing risk factors | Recommendations
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Testosterone is an androgen steroid hormone that is usually linked to male sexuality. It stimulates the growth of normal male sexual organs, leads to deepening of the male voice, stimulates facial and pubic hair growth, and is essential in the sexual behavior of men. Testosterone is made not only in the testes of men but also in the ovaries of women and in the adrenal glands of both men and women.
Abnormally high testosterone levels in women can lead to a variety of symptoms. Most often, women with high testosterone levels develop male pattern hair growth (hirsutism), especially on their faces and chests. More rarely, over time some women may experience virilization, which is increased muscle mass, redistribution of body fat, enlargement of the clitoris, deepening of the voice, male pattern baldness, acne, and increased perspiration. It is important to note that some women develop hirsutism without having a high testosterone level.
Increased testosterone levels in women are most often caused by polycystic ovaries. Less commonly, when testosterone levels are very elevated, ovarian cancer is a concern. Adrenal gland problems may contribute as well.
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Signs, symptoms & indicators of Elevated Testosterone Level, Female: | |  | | | | Lab Values - Hormones | Counter-indicators:
Having normal/having very low/having low testosterone levels | Symptoms - Female |
Enlarged clitoris | An enlarged clitoris is often due to a chronically elevated testosterone level. |
| Symptoms - Hair |
Balding | Symptoms - Head - Mouth/Oral |
Voice change | Symptoms - Mind - General |
A hard-driving personality | Excess secretion of testosterone (a hormone associated with male aggressive behavior) is reported in Type A personality patients. |
| Symptoms - Skin - General |
Excess perspiration |
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Conditions that suggest Elevated Testosterone Level, Female:
Risk factors for Elevated Testosterone Level, Female:
Recommendations for Elevated Testosterone Level, Female: | |  | | | | Botanical | Saw Palmetto (Serenoa repens) | Diet |
Sugars Avoidance / Reduction | While the following study did not use a study group of women diagnosed with PCOS (though some of the women in the study may also have been women with PCOS), the study's subjects were 104 women with the highest levels of testosterone out of 312 women screened. Thus, like women diagnosed with PCOS, these subjects tended to high androgen levels. The treatment group of the study received a highly controlled diet substantially restricting refined carbohydrates, included high quality protein, and provided omega-three and monounsaturated fatty acids. After eighteen weeks, the subjects with this modified diet showed a 25% increase in SHBG, a 19.5% decrease in testosterone, and a significant decrease in the amount of insulin released in response to a glucose challenge, compared to controls. The diet in the intervention group also accounted for a loss of about 7lbs, which may have actually been the most important factor in the reduction of testosterone. [Cancer Epidemiology Biomarkers and Prevention 2001; 10(1): pp.25-33] |
| Drug |
Conventional Drugs / Information | Troglitazone and metformin lower biologically available testosterone levels by approximately 25% in women with PCOS. This testosterone lowering correlates with the reduction in insulin levels. Resumption of ovulation has been reported in women receiving these agents alone or in combination with clomiphene citrate (Clomid). |
| Extract | Not recommended:
DIM (di-indolmethane)/I3C (Indole-3-Carbinol) | Aromatase inhibitors like DIM, Indole 3 carbinol, and chrysin should be avoided, as they will enhance any preexisting androgen / estrogen dominance. |
| Hormone |
Estrogen Replacement | Low estrogens allow the circulating androgens and testosterone to be more freely available and thus stimulate cells more. Increasing the circulating estrogen in the blood, by taking estrogens, will increase the proteins that bind the androgens and help decrease the effects of all androgens, whether the levels are normal or excessive. |
| Lab Tests/Rule-Outs |
Test / Monitor Hormone levels |
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KEY |  | Weak or unproven link |  |  | Strong or generally accepted link |  |  | Very strongly or absolutely counter-indicative |  |  | May do some good |  |  | Likely to help |  |  | Highly recommended |  |  | Reasonably likely to cause problems |
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