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  Monocytes Elevated  
 
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Contributing risk factors | Other conditions that may be present | Recommendations

 

Monocytes circulate in the blood and then enter the tissues and terminally differentiate into tissue macrophages, which are important antigen-presenting cells.

An increased percentage of monocytes may indicate:

  • Chronic inflammatory / immune disease: ulcerative colitis, regional enteritis, systemic lupus erythematosus, sarcoidosis
  • Protozoal infections: malaria, kala-azar, trypanosomiasis
  • Rickettsial infections: Rocky Mountain Spotted Fever, typhus
  • Bacterial infections: subacute bacterial endocarditis, tuberculosis, brucellosis, syphilis
  • Viral infection (for example, infectious mononucleosis, mumps, measles)
  • Congenital Gaucher disease, neoplastic monocytic leukemia, myeloid metaplasia, and recovery from agranulocytosis can all lead to increased level of monocytes also.

 

 
 

Risk factors for Monocytes Elevated:
 
 
Autoimmune  Ulcerative Colitis
  Lupus, SLE (Systemic Lupus Erythromatosis) / Risk
  Sarcoidosis

Infections

  Parasite Infection
  Tuberculosis
  Infectious Mononucleosis

Inflammation

  Chronic Inflammation

Tumors, Malignant

  Leukemia, Acute Myelogenous (AML)
 
 

Monocytes Elevated suggests the following may be present:
 
 
Inflammation  Chronic Inflammation
 
 

Recommendations for Monocytes Elevated:
 
 
Botanical  Antiinflammatory Combination Products
 
 


KEY
Weak or unproven link
Strong or generally accepted link
May do some good







GLOSSARY

Agranulocytosis:  Condition characterized by a marked decrease in the number of white blood cells called granulocytes.

Chronic:  Usually Chronic illness: Illness extending over a long period of time.

Enteritis:  Sometimes Enteritis regionalis: Localized inflammation of the intestine.

Leukemia:  Cancer of the lymph glands and bone marrow resulting in overproduction of white blood cells (related to Hodgkin's disease).

Mononucleosis:  An acute, infectious disease caused by the herpes virus, Epstein-Barr virus, with fever and inflamed swelling of the lymph nodes around the neck, under the arms, and in the groin.

Syphilis:  A sexually-transmitted disease, with symptoms in the early contagious stages being a sore on the genitalia, a rash, patches of flaking tissue, fever, a sore throat, and sores in the mouth or anus.

Tuberculosis:  Also known as TB, Consumption or "The White Plague", tuberculosis is an infectious disease caused by a bacterium called Mycobacterium tuberculosis, usually affecting the lungs but possibly also the brain, kidneys and bones. Patients may at first be symptom-free or experience a flu-like illness. In the secondary stage, there might be a slight fever, night sweats, weight loss, fatigue and various other symptoms, depending on the part of the body affected. Tuberculosis of the lung is usually associated with a dry cough that eventually leads to a productive cough with blood-stained sputum. There might also be chest pain and shortness of breath.

Ulcerative Colitis:  (Colitis ulcerosa): Ulceration of the colon and rectum, usually long-term and characterized by rectal bleeding or blood in the stool, frequent urgent diarrhea/bowel movements each day, abdominal pain.