Vitamin CoQ10 Need Last updated: Jul 17, 2008

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  Vitamin CoQ10 Need  
 

 
Conditions that suggest it | Contributing risk factors | Recommendations

 
 

The use of CoQ10 may be of benefit in several disorders. When supplementing with CoQ10, however, it is possible that a pre-existing CoQ10 deficiency may be necessary for any benefits to be seen. Measurement of plasma CoQ10 concentrations can assist in detecting deficiency states and thus serve as a dosage guide when oral supplementation is indicated.

 
 

Conditions that suggest Vitamin CoQ10 Need:
 
 
Lab Values  Elevated Total Cholesterol
 The statin drugs used to treat elevated blood cholesterol levels by blocking cholesterol synthesis also block CoQ10 synthesis. Supplemental CoQ10 should be considered in anyone on statin drugs.
 
 

Risk factors for Vitamin CoQ10 Need:
 
 
Supplements and Medications  (Past) cholesterol-lowering drug use
 HMG-CoA reductase inhibitors ("statin" drugs) used to treat elevated blood cholesterol levels by blocking cholesterol synthesis also block CoQ10 synthesis. The resulting lowering of blood CoQ10 level is due to the partially shared biosynthetic pathway of CoQ10 and cholesterol.

  History/absence of CoQ10 use

Counter-indicators:
  CoQ10 use
 
 

Recommendations for Vitamin CoQ10 Need:
 
 
Nutrient  CoQ10 (Ubiquin-one/ol)
 
 


KEY
Weak or unproven link
Strong or generally accepted link
Proven definite or direct link
Strongly counter-indicative
Likely to help

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GLOSSARY

Cholesterol:  A waxy, fat-like substance manufactured in the liver and found in all tissues, it facilitates the transport and absorption of fatty acids. In foods, only animal products contain cholesterol. An excess of cholesterol in the bloodstream can contribute to the development of atherosclerosis.