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| Diabetes Type I |
Last updated: May 12, 2008 |
Signs, symptoms and indicators | Conditions that suggest it | Contributing risk factors | Other conditions that may be present | It can lead to... | Recommendations
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Type 1 diabetes (often called Juvenile Onset Diabetes) is categorized as a childhood or young adult disease but rarely can occur at any age. Diabetes symptoms sometimes begin out of nowhere and can develop over just a few days. If the person doesn’t have a family history of the disease, the possibility of diabetes may not even be considered. Type 1 diabetes is rare in most Asian, African, and American Indian populations but more common in Caucasians.
Fortunately many of the common diabetic symptoms are similar to the more controllable form of the disease, Type 2 diabetes. Only 5-10% of the people expressing the classic diabetic symptoms will be diagnosed with Type 1 diabetes.
Previous research has suggested that children exposed to the insulin which can naturally be contained in cow's milk may develop antibodies to insulin. It is possible that in some genetically susceptible children, a continuous, even small-dose early exposure to bovine insulin in cow's milk may lead to loss of tolerance to insulin and subsequent Type 1 diabetes. Interestingly, where the child had a diabetic mother, rather than a diabetic father, this effect was less marked. {Science 155:26, June 26, 1999]
Vaccination with the meningitis vaccine was found to create more problems than it resolved, causing 54 cases of diabetes per 100,000 children injected. [Autoimmunity August 2002 Vol. 35 (4), pp. 247-253]
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Signs, symptoms & indicators of Diabetes Type I: | |  | | | | Symptoms - Food - Beverages | Frequent/constant thirst | Intense thirst and hunger are classic signs of diabetes. |
| Symptoms - Food - General |
Strong appetite
Not needing to eat during the night or night eating | Symptoms - General |
Constant fatigue | Symptoms - Head - Eyes/Ocular |
Vision disturbances |
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Conditions that suggest Diabetes Type I: | |  | | | | Metabolic | Problem Caused By Being Underweight | Organ Health |
Glomerular Disease | In both type 1 and type 2 diabetes, the first sign of deteriorating kidney function is the presence of small amounts of albumin in the urine, a condition called microalbuminuria. As kidney function declines, the amount of albumin in the urine increases, and microalbuminuria becomes full-fledged proteinuria. |
| Skin-Hair-Nails |
Dry skin | Signs of Type 1 Diabetes, as it progresses, may include dry skin, blurred vision, unexplained weight loss and a thin, malnourished appearance. |
| Symptoms - Glandular | Counter-indicators:
Absence of diabetes | Uro-Genital |
Increased Urinary Frequency
Erectile Dysfunction (ED, Impotence) | Overall, diabetes is the single most common condition linked with erectile dysfunction and it is estimated that nearly half of men with diabetes have some degree of erectile dysfunction. |
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Risk factors for Diabetes Type I: | |  | | | | Autoimmune | Autoimmune Tendency | Lab Values - Chemistries |
Very low C-Peptide level | C-Peptide levels will be absent or very low when little or no insulin is being produced by the pancreas. |
Low CO2 | Symptoms - Metabolic |
Recent unexplained weight loss |
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Diabetes Type I suggests the following may be present:
Diabetes Type I can lead to: | |  | | | | Circulation | Anemia, Megaloblastic | Relatives of people with Type 1 Diabetes, as well as the sufferers themselves, run a risk of developing celiac disease. The resulting inflammation and tissue damage reduces vitamin B12 absorption and may lead to Pernicious anemia, which occurs in approximately 1 in 50 adults with Type 1 Diabetes. |
| Metabolic |
Problem Caused By Being Underweight | Musculo-Skeletal |
Dupuytren's Contracture | Risks |
Increased Risk of Alzheimer's / Dementia | According to a new study in Neurology, diabetes mellitus may not only damage the function of the eye, limbs, kidneys, and heart - it may also impair the function of the brain and hasten the process of senile dementia.
Researchers found that diabetes mellitus nearly doubles the risk of developing both vascular dementia and Alzheimer's disease, according to the Rotterdam Study, a large prospective analysis which tracked dysglycemia and dementia in over 6000 individuals over age 55. Diagnosis of diabetes was based on World Health Organization criteria using a glucose tolerance test.
A related editorial called Alzheimer's a possible "brain-type diabetes." Besides damaging important blood vessel networks and increasing the risk of small "silent" strokes deep inside the brain, dysglycemia may be directly involved in the development of the neurofibrillary tangles, the clumping of nerves and fiber tissue inside the brain characteristic of Alzheimer's.
The researchers noted that advanced glycation endproducts (AGE), proteins damaged by chronically high blood sugar levels, are commonly found inside these tangles. "In brains of AD patients the receptor for AGE appears overexpressed," they noted. "Activation of this receptor leads to increased oxidative stress that may result in cellular damage."
Diabetes also disrupts insulin signaling to other cells in the body. This altered signaling may increase the activity of a neuronal enzyme that stimulates phosphorylated tau proteins to build up, a key trigger mechanism cited as one of the earliest signs of Alzheimer's.
NOTE: This study strongly suggests the important potential role of glycation products and insulin response, not just glucose levels, in the etiology of degenerative disease.
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| Skin-Hair-Nails |
Dry skin | Signs of Type 1 Diabetes, as it progresses, may include dry skin, blurred vision, unexplained weight loss and a thin, malnourished appearance. |
| Uro-Genital |
Increased Urinary Frequency
Erectile Dysfunction (ED, Impotence) | Overall, diabetes is the single most common condition linked with erectile dysfunction and it is estimated that nearly half of men with diabetes have some degree of erectile dysfunction. |
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Recommendations for Diabetes Type I: | |  | | | | Botanical | Evening Primrose Oil / GLA | A one-year study of 111 diabetic patients with mild neuropathy was conducted. The group was divided, with half receiving 480mg per day GLA and the other half receiving placebo. After one year the change for all 16 para-meters measured was more favorable for the GLA group than the placebo group, with statistical significance for 13 of the parameters. [Diabetes Care 1993;16: pp.8-15] |
Herbal Combinations | Liu Wei Di Huang Wan 0r Six Flavor Tea Pill is a formula for many yin deficient diseases and the standard formula for diabetes in China. |
| Miscellaneous |
Reading List | If you are considering insulin, beginning insulin, or have been on it for years but want to improve your control, the answers to your questions are finally here. This book by the authors of Pumping Insulin provides all the information you need to succeed on insulin.
Using Insulin - Everything You Need For Success With Insulin is by John Walsh PA CDE, Ruth Roberts MA, Chandrasekhar Varma MD FACE FACP, and Timothy Bailey MD FACE FACP |
| Nutrient |
Alpha Lipoic Acid | There is considerable evidence that alpha lipoic acid can be used to prevent and treat diabetes, both type I (juvenile diabetes) and type II (mature onset diabetes) and the complications of diabetes. |
| Vitamins |
Vitamin Niacinamide | Niacinamide improves ATP mitochondrial production in the face of diabetogenic chemicals and thus allows Islet cells to stay alive. The Type I honeymoon period can just be extended 12-18 months and insulin requirements may be less. |
Vitamin D | See the link between Autoimmune Tendency and Vitamin D. |
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KEY |  | Weak or unproven link |  |  | Strong or generally accepted link |  |  | Proven definite or direct link |  |  | Strongly counter-indicative |  |  | May do some good |  |  | Likely to help |
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